Myocardial Protection in Cardiac Surgery: How Limited Are the Options? A Comprehensive Literature Review
We provide a comprehensive and comparative overview of the effectiveness of each technique in achieving optimal cardioprotection and propose novel techniques for optimising myocardial protection in the future.
Sulfated Polysaccharides Effectively Inhibit SARS-Cov-2 In Vitro
To this end, we suggest that treatment of fucoidans, nebulized heparin, or possibly TriS-heparin in combination with or without current antiviral therapies, should be assessed first in human primary epithelial cells and then in human patients suffering from COVID-19.
Nitric Oxide Delivery During Cardiopulmonary Bypass Reduces Acute Kidney Injury: A Randomized Trial
NO administration in patients at moderate risk of renal complications undergoing elective cardiac surgery with CPB was associated with a lower incidence of AKI.
A Better Predictor of Acute Kidney Injury After Cardiac Surgery: The Largest Area Under the Curve Below the Oxygen Delivery Threshold During Cardiopulmonary Bypass
These data suggest that a high AUC below the is an important independent risk factor for AKI after cardiopulmonary bypass, which could be considered for risk prediction models of AKI.
Approach to Acute Cardiovascular Complications in COVID-19 Infection
This review discusses the presentation and management of patients with severe cardiac complications of COVID-19 disease, with an emphasis on a Heart-Lung team approach in patient management.
Extensive Cell Salvage and Postoperative Outcomes Following Thoracoabdominal and Descending Aortic Repair
Increased salvaged cell units were associated with adverse postoperative outcomes after D/TAAA repairs. Risk of renal failure and mortality increased proportionally to the salvaged cell units.
Commentary: Do-it-yourself Cell Salvage
The cause of complications observed with increased cell salvage is likely to remain enigmatic.
Provision of ECPR during COVID-19: Evidence, Equity, and Ethical Dilemmas
The logistics of patient selection, expedient cannulation, healthcare worker safety, and post-resuscitation care must be weighed against the ethical considerations.
Predictors and Outcomes of Ischemic Stroke After Cardiac Surgery
Stroke is a devastating complication after cardiac surgery that increases operative morbidity and mortality. Stroke with large vessel occlusion was associated with worse survival. However, early intervention did not impart a survival benefit.
Perioperative Management for Patients with von Willebrand Disease: Defining the Optimal Approach
This review provides an overview of the current evidence for the surgical management of patients with VWD and, summarises the optimal treatment approach during the perioperative period
COVID-19: Myocardial Injury in Survivors
In summary, myocardial injury is common in hospitalized COVID-19 patients and not exclusive to those with ACS or PE. In this single-centre, single-timepoint convalescent study, myocardial injury was associated with cardiac abnormalities detected by CMR where troponin elevation is unexplained even when cardiac function is normal.
A European Consensus Statement on The Use of Four-Factor Prothrombin Complex Concentrate for Cardiac and Non-Cardiac Surgical Patients
Tissue‐factor‐activated, factor VII‐dependent and heparin insensitive point‐of‐care tests may be used for peri‐operative monitoring and guiding of prothrombin complex concentrate therapy.