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Dexmedetomidine Pharmacokinetics and a New Dosing Paradigm in Infants Supported With Cardiopulmonary Bypass
Dexmedetomidine is increasingly used off-label in infants and children with cardiac disease during cardiopulmonary bypass (CPB) and in the postoperative period.
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Polarized Arrest With Warm or Cold Adenosine/Lidocaine Blood Cardioplegia is Equivalent to Hypothermic Potassium Blood Cardioplegia
This study tested the hypothesis that elective arrest in a polarized state with adenosine (400 mumol/L via adenosine triphosphate-sensitive potassium channel opening) and the Na + channel blocker lidocaine (750 mumol/L) as the arresting agents in blood cardioplegia provides cardioprotection comparable to standard hypothermic K + -blood cardioplegia.
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Ultrafiltration and Cardiopulmonary Bypass Associated Acute Kidney Injury: A Systematic Review and Meta-Analysis
UF in cardiac surgery is not associated with increased AKI incidence and may be safely used even in baseline chronic injury patients.
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