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Early Experience With Activated Recombinant Factor VII for Intractable Hemorrhage After Cardiovascular Surgery
. We report our experience with the use of activated recombinant factor VIIa (rFVIIa) as rescue therapy for patients with refractory postoperative hemorrhage.
Theoretical Treatise: Arterial Pressure during Aortic Surgery
This theoretical treatise predicts that blood pressure management should be temperature- and hematocrit-dependent. The target optimal blood pressure will vary during the course of surgery as a result of heating, cooling, and hemodilution.
Nitric Oxide Attenuates the Inflammatory Effects of Air During Extracorporeal Circulation
Cardiopulmonary bypass causes a systemic inflammatory response reaction that may contribute to postoperative complications. One cause relates to the air/blood interface from the extracorporeal circuit. The modulatory effects of blending nitric oxide (NO) gas into the ventilation/sweep gas of the membrane lung was studied in a porcine model of air-induced inflammation in which NO gas was added and compared with controls with or without an air/blood interface.
