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Argatroban Anticoagulation for Adult Extracorporeal Membrane Oxygenation: A Systematic Review
Argatroban infusion rates and anticoagulation target ranges showed substantial variations. The rational for divergent dosing and monitoring approaches are discussed in this paper. Argatroban appears to be a potential alternative to UFH in patients requiring ECMO. To definitively establish its safety, efficacy and ideal dosing strategy, larger prospective studies on well-defined patient populations are warranted.
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Diagnostic Score for Heparin-Induced Thrombocytopenia After Cardiopulmonary Bypass
Heparin-induced thrombocytopenia (HIT) occurs in nearly 3% of patients treated with heparin after cardiopulmonary bypass (CPB).
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