In Vivo and In Vitro Evaluation of the Heparin Management Test versus the Activated Coagulation Time for Monitoring Anticoagulation Level in Aprotinin-Treated Patients during Cardiac Surgery
Monitoring whole blood anticoagulation therapy with the activated coagulation time (kaolin ACT) and the heparin management test (HMT) were correlated in vivo with the plasma anti-activated factor X (anti-Xa) heparin concentration in patients who received variable doses of aprotinin and in vitro in the presence of increasing concentrations of aprotinin.
