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This review contains an analysis of all major randomized trials and registries on the number and cause of TAVR procedures that ended up in open-heart surgery and presents data to challenge the prerequisite of extracorporeal circulation system in the cath laboratory.
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Long-Term Safety and Effectiveness of Mechanical versus Biologic Aortic Valve Prostheses in Older Patients: Results from the Society of Thoracic Surgeons Adult Cardiac Surgery National Database
Among patients undergoing aortic valve replacement, long-term mortality rates were similar for those who received bioprosthetic versus mechanical valves.
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The Mechanisms of Cell Therapy for Clinical Investigations: An Urgent Need for Large-Animal Models
Evidence from experiments performed in animal models and from early-stage clinical trials demonstrate that the contractile performance of hearts with severe ischemic injury can be improved by transplanting a variety of cell types into the injured heart.
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