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The GP IIb/IIIa Inhibitor Abciximab (ReoPro((R))) Decreases Activation and Interaction of Platelets and Leukocytes During In Vitro Cardiopulmonary Bypass Simulation
The aim of this study was to investigate the effect of the GP IIb/IIIa inhibitor abciximab (ReoPro((R))) on the function and interaction of platelets and leukocytes during experimental CPB.
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Normoxic Re-Oxygenation Ameliorates End-Organ Injury After Cardiopulmonary Bypass
Normoxic reperfusion ameliorates cardiac, renal and neural injury compared with hyperoxic reperfusion in an in vivo animal model of CPB and cardioplegic arrest. This protective effect of normoxic reperfusion may be due to a reduction in signaling pathways for OS, inflammation, and apoptosis.
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Strategies to Reduce Hemostatic Activation During Cardiopulmonary Bypass
We evaluated whether a modified protocol for cardiopulmonary bypass (CPB) could reduced the systemic hemostatic activation associated with this procedure.
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