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Hyperoxia During Cardiopulmonary Bypass Does Not Decrease Cardiovascular Complications Following Cardiac Surgery: the CARDIOX Randomized Clinical Trial
Data on the benefit or or harmful effects of oxygen level on ischemic reperfusion injuries in cardiac surgery are insufficient.
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Extracorporeal Membrane Oxygenation: Indications, Technique and Contemporary Outcomes
Extracorporeal membrane oxygenation (ECMO) is an advanced form of temporary life support, to aid respiratory and/or cardiac function. It has been used since the early 1970s and is based on cardiopulmonary bypass technology and diverts venous blood through an extracorporeal circuit and returns it to the body after gas exchange through a semi-permeable membrane.
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Appropriate Clinical Trial Registration Is the Key to Transparent Reporting and Publication
In summary, since the advent of the ClinicalTrials.gov platform, the importance of trial registration has been recognized gradually but consistently throughout the globe. However, challenges remain, including the reluctance to participate on the part of pharmaceutical companies and a mindset among the individual researchers that registration is onerous and may result in the report of insignificant primary outcomes.
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