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Experimental Device Developed By Percutaneous Valve Technologies May Provide Alternative to Open Heart Surgery
Percutaneous Valve Technologies, Inc. (PVT) — a privately held medical technology company engaged in the development of a breakthrough device for the […]
High-Dose Polymerized Hemoglobin Fails to Alleviate Cardiac Ischemia/Reperfusion Injury Due to Induction of Oxidative Damage in Coronary Artery
This study was designed to investigate whether glutaraldehyde-polymerized human placenta hemoglobin (PolyPHb), a hemoglobin-based oxygen carrier (HBOC), can protect heart against cardiopulmonary bypass (CPB)-induced ischemia/reperfusion (I/R) injury or not and to elucidate the underlying mechanism.
Effect of the oXiris Membrane on Microcirculation after Cardiac Surgery under Cardiopulmonary Bypass: Study Protocol for A Randomised Controlled Trial (OXICARD Study)
Cytokine storm and endotoxin release during cardiac surgery with cardiopulmonary bypass (CPB) have been related to vasoplegic shock and organ dysfunction. We hypothesised that early (during CPB) cytokine adsorption with oXiris membrane for patients at high risk of inflammatory syndrome following cardiac surgery may improve microcirculation, endothelial function and outcomes.
