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Retrograde Autologous Priming Reduces Transfusion Requirements in Coronary Artery Bypass Surgery
The hypothesis was tested whether retrograde autologous priming (RAP) of the cardiopulmonary bypass system, compared to a standard primed system (NON-RAP group), results in less haemodilution and less transfusion of packed red blood cells.
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Increased Cerebral Mitochondrial Dysfunction and Reactive Oxygen Species with Cardiopulmonary Bypass
Exposure to 4 h of CPB resulted in a significant increase in cerebral mitochondrial ROS formation compared to shorter durations. Further study is needed to improve the understanding of cerebral mitochondrial health and its effects on the pathophysiology of neurological injury following exposure to CPB.
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Strategies to Minimize Intraoperative Blood Loss During Major Surgery
Reducing perioperative blood loss requires a multimodal and multidisciplinary approach. Although high‐quality evidence exists in certain areas, the overall evidence base for reducing intraoperative blood loss remains limited.
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