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Appropriate Clinical Trial Registration Is the Key to Transparent Reporting and Publication
In summary, since the advent of the ClinicalTrials.gov platform, the importance of trial registration has been recognized gradually but consistently throughout the globe. However, challenges remain, including the reluctance to participate on the part of pharmaceutical companies and a mindset among the individual researchers that registration is onerous and may result in the report of insignificant primary outcomes.
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The Influence of Aprotinin and Tranexamic Acid on Platelet Function and Postoperative Blood Loss in Cardiac Surgery
Antifibrinolytic drugs including aprotinin and tranexamic acid are currently used in cardiac surgery to reduce postoperative bleeding and transfusion requirements, and may have different effects on platelets.
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