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Is There Evidence that Fresh Frozen Plasma is Superior to Antithrombin Administration to Treat Heparin Resistance in Cardiac Surgery?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, 'in [patients with heparinresistance] is [treatment with FFP] superior [to antithrombin administration] in [achieving adequate anticoagulation to facilitate safe cardiopulmonary bypass]?'
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The Relationship Between Intraoperative Blood Transfusion and Postoperative Systemic Inflammatory Response Syndrome
Previous observations suggest that intraoperative blood transfusion (IBT) is a risk factor for adverse postoperative outcomes. IBT alters immune function and may predispose to systemic inflammatory response syndrome (SIRS).
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