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Perfusion NewswireBiologics ZoneCryoglobulinemia: Caution for Patients Undergoing Cardiac Surgery

Cryoglobulinemia: Caution for Patients Undergoing Cardiac Surgery

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We describe the case of a 65-year-old man with cryoglobulinemia undergoing cardiac surgery for combined mitral and aortic endocarditis, his preoperative management, and postoperative complications including purpura fulminans as the result of a cryoglobulinemia crisis, ending in death.

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Nitric Oxide Attenuates the Inflammatory Effects of Air During Extracorporeal Circulation

Cardiopulmonary bypass causes a systemic inflammatory response reaction that may contribute to postoperative complications. One cause relates to the air/blood interface from the extracorporeal circuit. The modulatory effects of blending nitric oxide (NO) gas into the ventilation/sweep gas of the membrane lung was studied in a porcine model of air-induced inflammation in which NO gas was added and compared with controls with or without an air/blood interface.

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