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A Novel Antidote-Controlled Anticoagulant Reduces Thrombin Generation and Inflammation and Improves Cardiac Function in Cardiopulmonary Bypass Surgery
Here we demonstrate that an anticoagulant aptamer-antidote pair targeting factor IXa can replace heparin and protamine in a porcine CPB model and also limit the adverse effects on thrombin generation, inflammation, and cardiac physiology associated with heparin and protamine use.
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Long-term Outcomes of Coronary Artery Bypass Grafting Patients Supported Preoperatively with an Intra-Aortic Balloon Pump
In patients supported preoperatively with an IABP, better early and long-term results were strongly related to younger age,
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Comparison of Transfusion Requirements for Conventional and Miniaturized Extracorporeal Circuits
The use of MECs can be expected to be associated with fewer red blood cell transfusions.
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