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Extracorporeal Membrane Oxygenation Network Organisation and Clinical Outcomes During the COVID-19 Pandemic in Greater Paris, France: A Multicentre Cohort Study
Beyond associations with similar factors to those reported on ECMO for non-COVID-19 ARDS, 90-day survival among ECMO-assisted patients with COVID-19 was strongly associated with a centre's experience in venovenous ECMO during the previous year. Early ECMO management in centres with a high venovenous ECMO case volume should be advocated, by applying centralisation and regulation of ECMO indications, which should also help to prevent a shortage of resources.
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Stenting and Minimally Invasive Bypass Surgery Equally Effective for Isolated High-grade Lesions
Minimally invasive bypass surgery and coronary stenting are equally effective in managing patients with isolated high-grade lesions of the proximal left anterior […]
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Toll-like Receptor 9 and the Inflammatory Response to Surgical Trauma and Cardiopulmonary Bypass
CPB, surgical trauma and ischemic perfusion injury trigger the release of circulating mtDNA that activates TLR-9, in turn stimulating a release of IL-6. Therefore, TLR-9 antagonists may attenuate this response and may provide a future therapeutic target whereby the systemic inflammatory response to cardiac surgery may be manipulated to improve clinical outcomes.
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