Previous reports of phenobarbital dosing during ECLS are reviewed and considerations for the dosing of anticonvulsant medications during extracorporeal support are discussed.
The present in vitro experiment with neonatal, infant, and pediatric CPB systems shows a variable recovery of routinely used drugs with significant differences between drugs, but not between system categories (with the exception of propofol).
On the last day of fellowship my mentor, Dr. Michael O’Connor, sat the fellows down and in 6 statements summarized what we each needed to know going into practice.
