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Postoperative Goal-Directed Therapy and Development of Acute Kidney Injury Following Major Elective Noncardiac Surgery: Post-Hoc Analysis of POM-O Randomized Controlled Trial
The role of goal-directed therapy (GDT) in preventing creatinine rise following noncardiac surgery is unclear. We performed a post-hoc analysis of a randomized controlled trial to assess the relationship between postoperative optimization of oxygen delivery and development of acute kidney injury (AKI)/creatinine rise following noncardiac surgery.
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Venous Obstruction and Cerebral Perfusion During Experimental Cardiopulmonary Bypass
To investigate the effects on cerebral perfusion by experimental venous congestion of the superior vena cava (SVC) during bicaval cardiopulmonary bypass (CPB) at 34 degrees C, pigs were subjected to SVC obstruction at levels of 75%, 50%, 25% and 0% of baseline SVC flow at two arterial flow levels (low, LQ, high, HQ).
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