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Application of Platelet-Rich Plasma in Non-Vascularied Bone Graft of Maxillofacial Surgery

Objective: To introduce the application of platelet-rich plasma (PRP) in non-vascularised bone grafts (NVBG) of maxillofacial surgery and its potential mechanism in recent years.


Methods: The latest articles were extensively retrieved, and the potential mechanism for PRP promotes the osteogenesis was discussed.


Results: PRP promotes osteogenesis when applied to NVBG, and the cytokine included in platelet is thought to be the ingredient for PRP’s effect. Some scholar has already applied PRP in the restoration of maxillofacial bone defect and got good results.


Conclusion: PRP has the potential to promotes osteogenesis, and more studies are needed for further understanding of its mechanism.


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