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Cerebral Air Emboli Differentially Alter Outcome After Cardiopulmonary Bypass in Rats Compared With Normal Circulation
This study was designed to investigate the effect of escalating volumes of CAE on survival and neurologic and histologic outcomes. In addition, the effect of xenon administration during CAE on these outcomes was determined.
Surviving and Thriving 1 Year After Cardiac Surgery: Frailty and Delirium Matter
Preoperative frailty alone did not negatively affect cardiac surgery patients’ functional outcomes up to 1 year, but coexisting frailty and POD led to substantial loss of independence on 3 to 4 ADLs and a 30.2-fold higher likelihood of dying 1 year after surgery. Because frailty led to a 4.9-fold increase in POD risk, frailty may serve as a presurgical screen to identify patients who would likely benefit from delirium prevention and functional recovery programs to maximize 1-year postsurgical outcomes.