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Toll-like Receptor 9 and the Inflammatory Response to Surgical Trauma and Cardiopulmonary Bypass
CPB, surgical trauma and ischemic perfusion injury trigger the release of circulating mtDNA that activates TLR-9, in turn stimulating a release of IL-6. Therefore, TLR-9 antagonists may attenuate this response and may provide a future therapeutic target whereby the systemic inflammatory response to cardiac surgery may be manipulated to improve clinical outcomes.
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Bypass Surgery Leaves Some Patients With Severe Problems
Although coronary artery bypass graft surgery improves the quality of life for most patients with extensive coronary artery disease, some patients continue […]
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Changing the Terminology from Kidney Replacement Therapy to Kidney Support Therapy
In this review, we discuss the use of various modes of kidney replacement therapy in treating renal and non‐renal complications to illustrate why kidney support therapy is a more appropriate terminology than renal replacement therapy.
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