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Platelet Preservation With a Glycoprotein IIb/IIIa Inhibitor in a Porcine Cardiopulmonary Bypass Model
We tested whether administration of FK633, a short-acting glycoprotein IIb/IIIa inhibitor, before median sternotomy and cardiopulmonary bypass was able to interrupt the platelet activation loop and thereby preserve platelet number and function.
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Blood Cell Adhesion to Arterial Filters Analysis by Scanning Electron Microscopy and Real-Time PCR Assay: Observational Clinical Study in Cardiac Surgery Patients
There was adhesion of blood elements, especially nucleated platelets, on all arterial filters studied. Although the arterial filter worked as a safety device, that possibly prevented arterial embolisation, it may also have caused greater hyperfibrinolysis during cardiopulmonary bypass.
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Goal-Directed Therapy Improves the Outcome of High-Risk Cardiac Patients Undergoing Off-Pump Coronary Artery Bypass
The present study was conducted to study the outcome benefits with the combined use of goal-directed therapy (GDT) with off-pump coronary artery bypass (OPCAB) as compared to the conventional hemodynamic management.
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