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Use of a Fixed, Body Weight-Unadjusted Loading Dose of Unfractionated Heparin for Extracorporeal Cardiopulmonary Resuscitation
A major complication of Extracorporeal cardiopulmonary resuscitation (ECPR) is bleeding; however, the optimal initial heparin dose and activated coagulation time (ACT) remain unknown. The aim of this study was to assess the appropriateness of our initial anticoagulation protocol.
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Plasma-Modified ACT Can Be Used to Monitor Bivalirudin (Angiomax) Anticoagulation for On-Pump Cardiopulmonary Bypass Surgery in a Patient with Heparin-Induced Thrombocytopenia
We report here the successful use of bivalirudin anticoagulation on pump, with no additional morbidity, and the first reported use of the plasma-modified ACT (activated clotting time) test, a simple modification of the standard ACT assay, to monitor the anticoagulant effect of bivalirudin.
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