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Neurologic Preservation by Na+-H+ Exchange Inhibition Prior to 90 Minutes of Hypothermic Circulatory Arrest
The effects of pretreatment with cariporide (HOE 642 Aventis Pharma, Strasbourg - Cedex, France), a Na+–H+ exchanger (NHE) blocker, were studied in a cerebral ischemia–reperfusion model of hypothermic arrest.
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Evaluation of the Impact of HMS Plus on Postoperative Blood Loss Compared with ACT Plus in Cardiac Surgery
HMS Plus did not reduce the mean blood-loss volume during the first 24 postoperative hours compared with ACT Plus. Its utility for potential transfusion rate reduction remains to be proven.
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Randomized Comparison Between Normothermic and Hypothermic Cardiopulmonary Bypass in Pediatric Open-Heart Surgery
The purpose of this study is to investigate the effect of cardiopulmonary bypass (CPB) temperature on myocardial reperfusion injury, oxidative stress, and inflammatory response in pediatric open heart surgery.
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