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There is evidence that, in adult cardiac surgical patients undergoing on-pump procedures, tranexamic acid (TXA) dose-dependently increases the risk of convulsive seizure (CS).
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The Effect of Levosimendan On Postoperative Bleeding and Blood Transfusion in Cardiac Surgical Patients: A PRISMA-Compliant Systematic Review and Meta-Analysis
This meta-analysis suggested that, peri-operative administration of LEVO was not associated with increased risks of post-operative bleeding and blood transfusion requirement in cardiac surgical patients.
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A Clinical Approach to Attenuate Hyperkalemia During Cardiopulmonary Bypass (EP Video)
Hyperkalemia during cardiopulmonary bypass (CPB) is a relatively frequent occurrence and is associated with decreased kidney perfusion and introduction of potassium (K+) during cardioplegia administration (22:11 minutes).
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