Effect of the oXiris Membrane on Microcirculation after Cardiac Surgery under Cardiopulmonary Bypass: Study Protocol for A Randomised Controlled Trial (OXICARD Study)
Cytokine storm and endotoxin release during cardiac surgery with cardiopulmonary bypass (CPB) have been related to vasoplegic shock and organ dysfunction. We hypothesised that early (during CPB) cytokine adsorption with oXiris membrane for patients at high risk of inflammatory syndrome following cardiac surgery may improve microcirculation, endothelial function and outcomes.