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Extracts of Adipose Derived Stem Cells Slows Progression in the R6/2 Model of Huntington’s Disease

Stem cell transplantation has been investigated as a therapeutic strategy to treat the Huntington's disease (HD). Considering clinical feasibility and safety, injection of cell-free extracts of ASCs (ASCs-E) could be effective and safe strategy for HD patients, comparable to the stem cell therapy. Findings from our study provide possible strategy to inhibit HD progression and reasonable resources for treatment.

Main Zone, Mobile Zone, Perfusion Zone

In Vivo and In Vitro Evaluation of the Heparin Management Test versus the Activated Coagulation Time for Monitoring Anticoagulation Level in Aprotinin-Treated Patients during Cardiac Surgery

Monitoring whole blood anticoagulation therapy with the activated coagulation time (kaolin ACT) and the heparin management test (HMT) were correlated in vivo with the plasma anti-activated factor X (anti-Xa) heparin concentration in patients who received variable doses of aprotinin and in vitro in the presence of increasing concentrations of aprotinin.

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