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Angiogenesis: Protein, Gene, or Cell Therapy?
The purpose of this review is to highlight the current progress, controversies, and challenges in the development of protein, gene, and cell-based approaches for clinical therapeutic angiogenesis.
Pericardial fluids or Cardiopulmonary Bypass-Is There a Major Culprit for Changes in Coagulation and Inflammation?
Direct recirculation of pericardial fluids rather than conventional CPB itself causes major intraoperative changes of some coagulation markers. Pericardial blood loss with direct recirculation should be kept to a minimum to avoid unnecessary activation of coagulation.
Platelet-Rich Plasma Stimulates Osteoblastic Differentiation in the Presence of BMPs
In the present study, we examined the effects of PRP on proliferation and osteoblast differentiation in vitro in the presence of bone morphogenetic proteins (BMPs). PRP and its soluble fraction stimulated osteoblastic differentiation of myoblasts and osteoblastic cells in the presence of BMP-2, BMP-4, BMP-6 or BMP-7.
