Hypothermic cardiopulmonary bypass (CPB) associated with cold myocardial protection is commonly used to perform neonatal cardiac surgery. Hypothermia is usually chosen to preserve the brain in case of failure of oxygen delivery whatever it may result from.
Safety features of Sorin S5 and Sorin CP5 will cover blood level monitoring, bubble detection and pressure safety features, as well as ramp up and ramp down features of the Sorin CP5 (12:00 minutes).
The uptake of isoflurane into blood via PMP oxygenators during CPB is severely limited. This should be taken into consideration in cases using such devices.