Cost-Effectiveness of Left Atrial Appendage Closure for Stroke Reduction in Atrial Fibrillation: Analysis of Pooled, 5-Year, Long-Term Data

Successful Antithrombin Administration in Andexanet Alfa-Associated Heparin Resistance

During routine CPB, high-dose unfractionated heparin (UFH) prevents consumptive coagulopathy and the formation of thrombi within the CPB circuit and the patient's circulation. Prior treatment with andexanet alfa can pose difficulties in achieving adequate anticoagulation during CPB with UFH. The administration of antithrombin, in combination with UFH, may overcome these difficulties.

Tranexamic Acid after Cardiopulmonary Bypass Does Not Increase Risk of Postoperative Seizures: A Retrospective Study

Administering TXA after bypass may reduce requirements for blood products without increasing risk of seizures following cardiac surgery.